Pharmacological Profile of the Purinergic P2Y Receptors That Modulate, in Response to ADPβS, the Vasodepressor Sensory CGRPergic Outflow in Pithed Rats

• मुख्य लेखकों: Alejandro D. Miguel-Martínez (लेखक), Juan Linares-Bedolla (लेखक), Belinda Villanueva-Castillo (लेखक), Kristian A. Haanes (लेखक), Antoinette MaassenVanDenBrink (लेखक), Carlos M. Villalón (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2023-03-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Calcitonin gene-related peptide (CGRP), an endogenous neuropeptide released from perivascular sensory nerves, exerts a powerful vasodilatation. Interestingly, adenosine triphosphate (ATP) stimulates the release of CGRP by activation of prejunctional P2X_2/3 receptors, and adeno...