lncRNA ZEB1-AS1 Was Suppressed by p53 for Renal Fibrosis in Diabetic Nephropathy

• Main Authors: Juan Wang (Author), Jian Pang (Author), Huiling Li (Author), Jie Long (Author), Fang Fang (Author), Junxiang Chen (Author), Xuejin Zhu (Author), Xudong Xiang (Author), Dongshan Zhang (Author)
• Format: Book
• Published: Elsevier, 2018-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The role of p53 in renal fibrosis is still controversial, and its underlying mechanisms remain not clear. Here, we showed that the pharmacological inhibition and genetic deletion of p53 in proximal tubular cells can attenuate renal dysfunction, tubular epithelial disruption, and interstitial fibrosi...