CHMP5 attenuates osteoarthritis via inhibiting chondrocyte apoptosis and extracellular matrix degradation: involvement of NF-κB pathway

• Glavni autori: Weilu Gao (Autor), Rui Liu (Autor), Keke Huang (Autor), Wenhan Fu (Autor), Anquan Wang (Autor), Gongwen Du (Autor), Hao Tang (Autor), Li Yin (Autor), Zongsheng S. Yin (Autor)
• Format: Knjiga
• Izdano: BMC, 2024-04-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Abstract Background Osteoarthritis (OA), the most common joint disease, is linked with chondrocyte apoptosis and extracellular matrix (ECM) degradation. Charged multivesicular body protein 5 (CHMP5), a member of the multivesicular body, has been reported to serve as an anti-apoptotic protein to part...