CHMP5 attenuates osteoarthritis via inhibiting chondrocyte apoptosis and extracellular matrix degradation: involvement of NF-κB pathway

CHMP5 attenuates osteoarthritis via inhibiting chondrocyte apoptosis and extracellular matrix degradation: involvement of NF-κB pathway

Abstract Background Osteoarthritis (OA), the most common joint disease, is linked with chondrocyte apoptosis and extracellular matrix (ECM) degradation. Charged multivesicular body protein 5 (CHMP5), a member of the multivesicular body, has been reported to serve as an anti-apoptotic protein to part...

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Main Authors: Weilu Gao (Author), Rui Liu (Author), Keke Huang (Author), Wenhan Fu (Author), Anquan Wang (Author), Gongwen Du (Author), Hao Tang (Author), Li Yin (Author), Zongsheng S. Yin (Author)
Format: Book
Published: BMC, 2024-04-01T00:00:00Z.
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