CHMP5 attenuates osteoarthritis via inhibiting chondrocyte apoptosis and extracellular matrix degradation: involvement of NF-κB pathway

• Main Authors: Weilu Gao (Author), Rui Liu (Author), Keke Huang (Author), Wenhan Fu (Author), Anquan Wang (Author), Gongwen Du (Author), Hao Tang (Author), Li Yin (Author), Zongsheng S. Yin (Author)
• Format: Book
• Published: BMC, 2024-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Osteoarthritis (OA), the most common joint disease, is linked with chondrocyte apoptosis and extracellular matrix (ECM) degradation. Charged multivesicular body protein 5 (CHMP5), a member of the multivesicular body, has been reported to serve as an anti-apoptotic protein to part...