Repurposing Disulfiram as an Antifungal Agent: Development of a New Disulfiram Vaginal Mucoadhesive Gel

• Main Authors: Maria Lajarin-Reinares (Author), Iria Naveira-Souto (Author), Mireia Mallandrich (Author), Joaquim Suñer-Carbó (Author), Montserrat Llagostera Casas (Author), Maria Angels Calvo (Author), Francisco Fernandez-Campos (Author)
• Format: Book
• Published: MDPI AG, 2023-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Alternative formulations need to be developed to improve the efficacy of treatments administered via the vaginal route. Mucoadhesive gels with disulfiram, a molecule that was originally approved as an antialcoholism drug, offer an attractive alternative to treat vaginal candidiasis. The aim of the c...