Intravitreous delivery of melatonin affects the retinal neuron survival and visual signal transmission: in vivo and ex vivo study

• Main Authors: Ye Tao (Author), Bang Hu (Author), Zhao Ma (Author), Haijun Li (Author), Enming Du (Author), Gang Wang (Author), Biao Xing (Author), Jie Ma (Author), Zongming Song (Author)
• Formato: Livro
• Publicado em: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Intravitreal delivery can maximize the intensity of therapeutic agents and extend their residence time within ocular tissue. Melatonin is a lipophilic molecule that crosses freely biological barriers and cell membranes. This study intends to investigate the effects of intravitreally delivered melato...