3-Hydroxypropane-1,2-Diyl Dipalmitoleate-A Natural Compound with Dual Roles (CB1 Agonist/FAAH1 Blocker) in Inhibiting Ovarian Cancer Cell Line

• Main Authors: Christina Vijayaraghavan Sathynathan (Author), Lakshmi Sundaram Raman (Author), Sivamurugan Vajiravelu (Author), Thirumal D. Kumar (Author), Thyagarajan Sadras Panchatcharam (Author), Gopinathan Narasimhan (Author), George C. Priya Doss (Author), Mary Elizabeth Gnanambal Krishnan (Author)
• Format: Book
• Published: MDPI AG, 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Though it was once known that upregulated Cannabinoid Receptor (CB1) and downregulated Fatty Acid Amide Hydrolase (FAAH1) are associated with tumour aggressiveness and metastasis, it is now clear that upregulated CB1 levels more than a certain point cause accumulation of ceramide and directs cells t...