Oscillatory shear stress promotes angiogenic effects in arteriovenous malformations endothelial cells

• Main Authors: Jeong Yeop Ryu (Author), Yun Hyun Kim (Author), Joon Seok Lee (Author), Jeong Woo Lee (Author), Eun Jung Oh (Author), Hyun Mi Kim (Author), Seok-Jong Lee (Author), Jongmin Lee (Author), Sang Yub Lee (Author), Seung Huh (Author), Ji Yoon Kim (Author), Saewon Im (Author), Ho Yun Chung (Author)
• Format: Book
• Published: BMC, 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Vascular endothelial cells (ECs) are subject to continuous shear stress due to blood circulation. Mechanical stress due to high shear flow can also cause arteriovenous malformation (AVM) when ECs respond hyper-sensitively to shear flow. This study was conducted to test the hypoth...