The activation of the G-protein-coupled estrogen receptor promotes the aggressiveness of MDA-MB231 cells by targeting the IRE1α/TXNIP pathway

Background and purpose: This study investigated modulating the G protein-coupled estrogen receptor (GPER) on the IRElα/TXNIP pathway and its role in drug resistance in MDA-MB231 cells. Experimental approach: To determine the optimal concentrations of G1 and 4-hydroxytamoxifen (TAM), GPER expression...

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Autors principals: Maryam Mohammad-Sadeghipour (Autor), Mohammad Hadi Nematollahi (Autor), Hassan Ahmadinia (Autor), Mohammad Reza Hajizadeh (Autor), Mehdi Mahmoodi (Autor)
Format: Llibre
Publicat: Wolters Kluwer Medknow Publications, 2024-10-01T00:00:00Z.
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