Anticancer active trifluoromethylated fused triazinones are safe for early-life stages of zebrafish (Danio rerio) and reveal a proapoptotic action

• Huvudskapare: Małgorzata Sztanke (Författare, medförfattare), Jolanta Rzymowska (Författare, medförfattare), Krzysztof Sztanke (Författare, medförfattare)
• Materialtyp: Bok
• Publicerad: Taylor & Francis Group, 2021-01-01T00:00:00Z.
• Ämnen: article
• Länkar: Connect to this object online.

The main purpose of this investigation was to evaluate the effect of anticancer active compounds (I-VIII) on zebrafish development in order to select the safest molecules. Larval mortality, embryo hatchability and malformations were end-points used to assess the acute toxicity among embryos and larv...