Indirect Comparison of Lanadelumab and Intravenous C1-INH Using Data from the HELP and CHANGE Studies: Bayesian and Frequentist Analyses

• Main Authors: Joan Mendivil (Author), Mia Malmenäs (Author), Katrin Haeussler (Author), Matthias Hunger (Author), Gagan Jain (Author), Giovanna Devercelli (Author)
• Format: Book
• Published: Adis, Springer Healthcare, 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Hereditary angioedema (HAE) with C1-esterase inhibitor (C1-INH) deficiency is a rare disease associated with painful, potentially fatal swelling episodes affecting subcutaneous or submucosal tissues. HAE attacks recur with unpredictable severity and frequency throughout patients&...