Indoxyl sulfate aggravates podocyte damage through the TGF-β1/Smad/ROS signaling pathway

• Prif Awduron: Miao Jia (Awdur), Lihua Lin (Awdur), Kang Xun (Awdur), Damei Li (Awdur), Weijiang Wu (Awdur), Shaobo Sun (Awdur), Hong Qiu (Awdur), Donghua Jin (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: Karger Publishers, 2024-05-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

Introduction: Hyperglycaemia induces the production of a large quantity of reactive oxygen species (ROS) and activates the transforming growth factor β1(TGF-β1)/Smad signalling pathway, which is the main initiating factor in the formation of diabetic nephropathy. Indoxyl sulfate (IS) is a protein-bi...