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Antiproliferative effects of 13α/β-steroids on triple-negative MDA-MB-231 breast cancer cells: unraveling intracellular signaling without ERα

Abstract This study aimed to investigate the activities of novel 20(R)-3,20-dihydroxy-19-norpregn-1,3,5(10)-trienes (kuz7 and kuz8b) of natural 13β- and epimeric 13α-series against triple-negative MDA-MB-231 breast cancer cells. High antiproliferative activity of synthesized compounds kuz8b and kuz7...

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Main Authors: Alexander M. Scherbakov (Author), Yury V. Kuznetsov (Author), Margarita A. Yastrebova (Author), Alvina I. Khamidullina (Author), Danila V. Sorokin (Author), Maria O. Tserfas (Author), Inna S. Levina (Author)
Format: Book
Published: Universidade de São Paulo, 2023-05-01T00:00:00Z.
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