Altered H19/miR‐675 expression in skeletal muscle is associated with low muscle mass in community‐dwelling older adults

• Main Authors: Elie Antoun (Author), Eugenia Migliavacca (Author), Emma S Garratt (Author), Sheila J Barton (Author), Phil Titcombe (Author), Leo D Westbury (Author), Alica Baczynska (Author), Richards Dodds (Author), Helen C Roberts (Author), Avan A Sayer (Author), Sarah Shaw (Author), H.E. Syddall (Author), Allan Sheppard (Author), Craig McFarlane (Author), Neerja Karnani (Author), Terrence Forrester (Author), Cyrus Cooper (Author), Jerome N Feige (Author), Harnish P Patel (Author), Keith M Godfrey (Author), Karen A Lillycrop (Author), the EpiGen Global Research Consortium (Author)
• Format: Book
• Published: Wiley, 2021-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Despite increasing knowledge of the pathogenesis of muscle ageing, the molecular mechanisms are poorly understood. Based on an expression analysis of muscle biopsies from older Caucasian men, we undertook an in‐depth analysis of the expression of the long non‐coding RNA, H19, to...