The Target Differences of Anti-Tumorigenesis Potential of Curcumin and its Analogues Against HER-2 Positive and Triple-Negative Breast Cancer Cells

• Main Authors: Edy Meiyanto (Author), Ulfatul Husnaa (Author), Ria Fajarwati Kastian (Author), Herwandhani Putri (Author), Yonika Arum Larasati (Author), Annisa Khumaira (Author), Dyaningtyas Dewi Putri Pamungkas (Author), Riris Istighfari Jenie (Author), Masashi Kawaichi (Author), Beni Lestari (Author), Takashi Yokoyama (Author), Jun-ya Kato (Author)
• Format: Book
• Published: Tabriz University of Medical Sciences, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose: The current study aims to evaluate the in vitro cytotoxic and cell migration effects of synthetic curcumin and its analogues on HER2 and nuclear factor kappa B (NFκB) pathways, as well as the in vivo inhibitory effect on cancer growth of metastatic breast cancer. Methods: Cell viability, pr...