Effects of temperature and wavelength choice on in-situ dissolution test of Cimetidine tablets

• Main Authors: Xin-Xia Li (Author), Yan Wang (Author), Ping-Ping Xu (Author), Qi-Zhou Zhang (Author), Kun Nie (Author), Xu Hu (Author), Bin Kong (Author), Li Li (Author), Jian Chen (Author)
• Format: Book
• Published: Elsevier, 2013-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The effects of temperature and wavelength choice on in-situ dissolution test instrument of Cimetidine were studied. Absorbance (A)<1.0 is required when using a fiber-optic dissolution test system. The detection wavelength of λmax (218 nm) was replaced by 244 nm to carry out this test. The abso...