First-in-human study to assess the safety, tolerability, pharmacokinetics and immunogenicity of DS002, an anti-nerve growth factor monoclonal antibody

• Main Authors: Tingting Ma (Author), Bei Cao (Author), Lei Huang (Author), Yuanxun Yang (Author), Yan Geng (Author), Pinhao Xie (Author), Yu Zhao (Author), Hui Lin (Author), Kun Wang (Author), Chunhe Wang (Author), Runbin Sun (Author), Juan Li (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose: To evaluate the safety, tolerability, pharmacokinetics and immunogenicity of DS002 injection, an anti-nerve growth factor (anti-NGF) monoclonal antibody for treating pain conditions, in healthy Chinese subjects.Methods: This study was a single-center, randomized, double-blind, single-dose e...