Mechanisms Underlying the Anti-inflammatory Effects of the Ca2+/Calmodulin Antagonist CV-159 in Cultured Vascular Smooth Muscle Cells
CV-159 is a unique dihydropyridine Ca2+antagonist with an anti-calmodulin (CaM) action. A pathogenic feature of atherosclerosis is vascular inflammatory change. In the present study, we examined whether CV-159 exerts protective effects on smooth muscle inflammatory responses. After pretreatment of r...
Saved in:
Main Authors: | Tatsuya Usui (Author), Hideyuki Yamawaki (Author), Masato Kamibayashi (Author), Muneyoshi Okada (Author), Yukio Hara (Author) |
---|---|
Format: | Book |
Published: |
Elsevier,
2010-01-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
CV-159, a Unique Dihydropyridine Derivative, Prevents TNF-Induced Inflammatory Responses in Human Umbilical Vein Endothelial Cells
by: Tatsuya Usui, et al.
Published: (2010) -
Methylglyoxal Inhibits Smooth Muscle Contraction in Isolated Blood Vessels
by: Masashi Mukohda, et al.
Published: (2009) -
Methylglyoxal Accumulation in Arterial Walls Causes Vascular Contractile Dysfunction in Spontaneously Hypertensive Rats
by: Masashi Mukohda, et al.
Published: (2012) -
Exploring Mechanisms of Diabetes-Related Macrovascular Complications: Role of Methylglyoxal, a Metabolite of Glucose on Regulation of Vascular Contractility
by: Masashi Mukohda, et al.
Published: (2012) -
Methylglyoxal Augments Angiotensin II-Induced Contraction in Rat Isolated Carotid Artery
by: Masashi Mukohda, et al.
Published: (2010)