Inhibition of Growth and Gene Expression by PNA-peptide Conjugates in Streptococcus pyogenes

• Main Authors: Nadja Patenge (Author), Roberto Pappesch (Author), Franziska Krawack (Author), Claudia Walda (Author), Mobarak Abu Mraheil (Author), Anette Jacob (Author), Torsten Hain (Author), Bernd Kreikemeyer (Author)
• Format: Book
• Published: Elsevier, 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

While Streptococcus pyogenes is consistently susceptible toward penicillin, therapeutic failure of penicillin treatment has been reported repeatedly and a considerable number of patients exhibit allergic reactions to this substance. At the same time, streptococcal resistance to alternative antibioti...