Neuroprotection Against NMDA-Induced Retinal Damage by Philanthotoxin-343 Involves Reduced Nitrosative Stress

• Main Authors: Mohamad Haiqal Nizar Mohamad (Author), Izuddin Fahmy Abu (Author), Muhammad Fattah Fazel (Author), Renu Agarwal (Author), Igor Iezhitsa (Author), Norsham Juliana (Author), Ian R. Mellor (Author), Henrik Franzyk (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

N-methyl-D-aspartate receptor (NMDAR) overstimulation is known to mediate neurodegeneration, and hence represents a relevant therapeutic target for neurodegenerative disorders including glaucoma. This study examined the neuroprotective effects of philanthotoxin (PhTX)-343 against NMDA-induced retina...