Sex-Biased Associations of Circulating Ferroptosis Inhibitors with Reduced Lipid Peroxidation and Better Neurocognitive Performance in People with HIV

• Main Authors: Harpreet Kaur (Author), Ravi K. Alluri (Author), Kunling Wu (Author), Robert C. Kalayjian (Author), William S. Bush (Author), Frank J. Palella (Author), Susan L. Koletar (Author), Corrilynn O. Hileman (Author), Kristine M. Erlandson (Author), Ronald J. Ellis (Author), Roger J. Bedimo (Author), Babafemi O. Taiwo (Author), Katherine K. Tassiopoulos (Author), Asha R. Kallianpur (Author)
• Format: Book
• Published: MDPI AG, 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ferroptosis is implicated in viral neuropathogenesis and may underlie HIV-associated neurocognitive impairment (NCI). Emerging data also suggest differences in brain iron transport by sex. We hypothesized that circulating ferritins that inhibit ferroptosis associate with neurocognitive function and...