Aryl Hydrocarbon Receptor (AhR)-Mediated Signaling in iPSC-Derived Human Motor Neurons

• Main Authors: Saima Jalil Imran (Author), Barbora Vagaska (Author), Jan Kriska (Author), Miroslava Anderova (Author), Mario Bortolozzi (Author), Gino Gerosa (Author), Patrizia Ferretti (Author), Radim Vrzal (Author)
• Format: Book
• Published: MDPI AG, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Exposure to environmental pollutants and endogenous metabolites that induce aryl hydrocarbon receptor (AhR) expression has been suggested to affect cognitive development and, particularly in boys, also motor function. As current knowledge is based on epidemiological and animal studies, in vitro mode...