Prediction of Synergistic Drug Combinations for Prostate Cancer by Transcriptomic and Network Characteristics

• Main Authors: Shiqi Li (Author), Fuhui Zhang (Author), Xiuchan Xiao (Author), Yanzhi Guo (Author), Zhining Wen (Author), Menglong Li (Author), Xuemei Pu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Prostate cancer (PRAD) is a major cause of cancer-related deaths. Current monotherapies show limited efficacy due to often rapidly emerging resistance. Combination therapies could provide an alternative solution to address this problem with enhanced therapeutic effect, reduced cytotoxicity, and dela...