Involvement of circRNAs in Proinflammatory Cytokines-Mediated β-Cell Dysfunction
Aim. During the initial stage of type 1 diabetes, prolonged exposure of pancreatic β-cell to proinflammatory cytokines such as IL-1β, TNF-α, and IFN-γ results in a decreased capacity to produce and release insulin, as well as cell loss by apoptosis. Circular RNAs (circRNAs) are a new class of endoge...
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Hindawi Limited,
2021-01-01T00:00:00Z.
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