Pim1 knockout alleviates sarcopenia in aging mice via reducing adipogenic differentiation of PDGFRα+ mesenchymal progenitors

• المؤلفون الرئيسيون: Guo‐kai Shang (مؤلف), Lu Han (مؤلف), Zhi‐hao Wang (مؤلف), Ming Song (مؤلف), Di Wang (مؤلف), Yan‐min Tan (مؤلف), Yi‐hui Li (مؤلف), Yu‐lin Li (مؤلف), Wei Zhang (مؤلف), Ming Zhong (مؤلف)
• التنسيق: كتاب
• منشور في: Wiley, 2021-12-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Abstract Background Sarcopenia widely exists in elderly people and triggers numerous age‐related events. The essential pathologic change lies in the increased intramuscular adipose tissue after aging with no exception to non‐obese objects. Pim1 appears to be associated with adipogenic differentiatio...