Oxidative Stress and Inflammatory Modulation of Ca²⁺ Handling in Metabolic HFpEF-Related Left Atrial Cardiomyopathy

• Main Authors: David Bode (Author), Yan Wen (Author), Niklas Hegemann (Author), Uwe Primessnig (Author), Abdul Parwani (Author), Leif-Hendrik Boldt (Author), Burkert M. Pieske (Author), Frank R. Heinzel (Author), Felix Hohendanner (Author)
• Format: Book
• Published: MDPI AG, 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Metabolic syndrome-mediated heart failure with preserved ejection fraction (HFpEF) is commonly accompanied by left atrial (LA) cardiomyopathy, significantly affecting morbidity and mortality. We evaluate the role of reactive oxygen species (ROS) and intrinsic inflammation (TNF-α, IL-10) related to d...