AlbuCORE: an albumin-based molecular scaffold for multivalent biologics design

• Main Authors: Mario Sanches (Author), Igor D'Angelo (Author), Maria Jaramillo (Author), Jason Baardsnes (Author), John Zwaagstra (Author), Joe Schrag (Author), Ian Schoenhofen (Author), Mauro Acchione (Author), Sam Lawn (Author), Grant Wickman (Author), Nina Weisser (Author), David K. Y. Poon (Author), Gordon Ng (Author), Surjit Dixit (Author)
• Format: Book
• Published: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

As biologics have become a mainstay in the development of novel therapies, protein engineering tools to expand on their structural advantages, namely specificity, affinity, and valency are of interest. Antibodies have dominated this field as the preferred scaffold for biologics development while the...