AlbuCORE: an albumin-based molecular scaffold for multivalent biologics design

• Главные авторы: Mario Sanches (Автор), Igor D'Angelo (Автор), Maria Jaramillo (Автор), Jason Baardsnes (Автор), John Zwaagstra (Автор), Joe Schrag (Автор), Ian Schoenhofen (Автор), Mauro Acchione (Автор), Sam Lawn (Автор), Grant Wickman (Автор), Nina Weisser (Автор), David K. Y. Poon (Автор), Gordon Ng (Автор), Surjit Dixit (Автор)
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• Опубликовано: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Предметы: article
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As biologics have become a mainstay in the development of novel therapies, protein engineering tools to expand on their structural advantages, namely specificity, affinity, and valency are of interest. Antibodies have dominated this field as the preferred scaffold for biologics development while the...