The neuromedin U system: Pharmacological implications for the treatment of obesity and binge eating behavior

• Main Authors: Luca Botticelli (Author), Emanuela Micioni Di Bonaventura (Author), Fabio Del Bello (Author), Gianfabio Giorgioni (Author), Alessandro Piergentili (Author), Wilma Quaglia (Author), Alessandro Bonifazi (Author), Carlo Cifani (Author), Maria Vittoria Micioni Di Bonaventura (Author)
• Format: Book
• Published: Elsevier, 2023-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Neuromedin U (NMU) is a bioactive peptide produced in the gut and in the brain, with a role in multiple physiological processes. NMU acts by binding and activating two G protein coupled receptors (GPCR), the NMU receptor 1 (NMU-R1), which is predominantly expressed in the periphery, and the NMU rece...