Conjugates of Chloramphenicol Amine and Berberine as Antimicrobial Agents

• Main Authors: Julia A. Pavlova (Author), Andrey G. Tereshchenkov (Author), Pavel A. Nazarov (Author), Dmitrii A. Lukianov (Author), Dmitry A. Skvortsov (Author), Vladimir I. Polshakov (Author), Byasilya F. Vasilieva (Author), Olga V. Efremenkova (Author), Mikhail Y. Kaiumov (Author), Alena Paleskava (Author), Andrey L. Konevega (Author), Olga A. Dontsova (Author), Ilya A. Osterman (Author), Alexey A. Bogdanov (Author), Natalia V. Sumbatyan (Author)
• Format: Book
• Published: MDPI AG, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In order to obtain antimicrobial compounds with improved properties, new conjugates comprising two different biologically active agents within a single chimeric molecule based on chloramphenicol (CHL) and a hydrophobic cation were synthesized and studied. Chloramphenicol amine (CAM), derived from th...