Dual-responsive supramolecular photodynamic nanomedicine with activatable immunomodulation for enhanced antitumor therapy

• Main Authors: Siqin He (Author), Lulu Wang (Author), Dongxu Wu (Author), Fan Tong (Author), Huan Zhao (Author), Hanmei Li (Author), Tao Gong (Author), Huile Gao (Author), Yang Zhou (Author)
• Format: Book
• Published: Elsevier, 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A major challenge facing photodynamic therapy (PDT) is that the activity of the immune-induced infiltrating CD8+ T cells is subject to the regulatory T lymphocytes (Tregs), leaving the tumor at risk of recurrence and metastasis after the initial ablation. To augment the antitumor response and reprog...