Selective Estrogen Receptor Modulator-Like Activities of Herba epimedii Extract and its Interactions With Tamoxifen and Raloxifene in Bone Cells and Tissues

• Main Authors: Liping Zhou (Author), Ka-Ying Wong (Author), Wenxuan Yu (Author), Christina Chui-Wa Poon (Author), Huihui Xiao (Author), Chi-On Chan (Author), Daniel Kam-Wah Mok (Author), Yan Zhang (Author), Man-Sau Wong (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Herbaepimedii (HEP), a kidney-tonifying herb, has been commonly used alone or in formula for strengthening kidney function and treating bone disorders. Its bone protective activity has been demonstrated to be via estrogen receptor (ERs). HEP activates the phosphorylation of ERα in an estrogen respon...