DEVELOPMENT, IN-VITRO AND EX-VIVO EVALUATION OF MUCO-ADHESIVE BUCCAL TABLETS OF HYDRALAZINE HYDROCHLORIDE

• मुख्य लेखकों: Kumara Swamy Samanthula (लेखक), Mahendra Kumar CB (लेखक), Agaiah Goud Bairi (लेखक), Shobha Rani Satla (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Universidade de São Paulo, 2022-04-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abstract Hydralazine hydrochloride is an anti-hypertensive drug. The drug has poor oral bioavailability (BA) of about 30- 50% due to extensive first-pass metabolism. Hence, the buccal delivery was used to enhance the BA of hydralazine hydrochloride. Buccal muco-adhesive tablets were prepared by dire...