Huperzine A targets Apolipoprotein E: A potential therapeutic drug for diabetic nephropathy based on omics analysis

• Main Authors: Xiangjun Chen (Author), Ying Zhang (Author), Zhongkai Cao (Author), Yue Wang (Author), Mengqiu Liao (Author), Yuelin Guan (Author), Caifeng Zhu (Author), Wenmin Wang (Author), Wunan Huang (Author), Wei Li (Author), Yingping Xiao (Author), Yayu Li (Author), Jiazhen Yin (Author), Yuhan Ding (Author), Qinghua Peng (Author), Lidan Hu (Author)
• Format: Book
• Published: Elsevier, 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aims: Diabetic nephropathy (DN) is a major complication of diabetes mellitus (DM) without curative interventions currently. Huperzine A (Hup A), a natural alkaloid, has demonstrated significant hypoglycemic and anti-inflammatory effects. We aim to investigate the protective effects of Hup A on DN an...