Monitoring the Bystander Killing Effect of Human Multipotent Stem Cells for Treatment of Malignant Brain Tumors

• Main Authors: Cindy Leten (Author), Jesse Trekker (Author), Tom Struys (Author), Valerie D. Roobrouck (Author), Tom Dresselaers (Author), Greetje Vande Velde (Author), Ivo Lambrichts (Author), Catherine M. Verfaillie (Author), Uwe Himmelreich (Author)
• Format: Book
• Published: Hindawi Limited, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Tumor infiltrating stem cells have been suggested as a vehicle for the delivery of a suicide gene towards otherwise difficult to treat tumors like glioma. We have used herpes simplex virus thymidine kinase expressing human multipotent adult progenitor cells in two brain tumor models (hU87 and Hs683)...