Morphological and functional correlates of vestibular synaptic deafferentation and repair in a mouse model of acute-onset vertigo

• Main Authors: Raphaelle Cassel (Author), Pierrick Bordiga (Author), Julie Carcaud (Author), François Simon (Author), Mathieu Beraneck (Author), Anne Le Gall (Author), Anne Benoit (Author), Valentine Bouet (Author), Bruno Philoxene (Author), Stéphane Besnard (Author), Isabelle Watabe (Author), David Pericat (Author), Charlotte Hautefort (Author), Axel Assie (Author), Alain Tonetto (Author), Jonas Dyhrfjeld-Johnsen (Author), Jordi Llorens (Author), Brahim Tighilet (Author), Christian Chabbert (Author)
• Format: Book
• Published: The Company of Biologists, 2019-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Damage to cochlear primary afferent synapses has been shown to be a key factor in various auditory pathologies. Similarly, the selective lesioning of primary vestibular synapses might be an underlying cause of peripheral vestibulopathies that cause vertigo and dizziness, for which the pathophysiolog...