Quantitative mass spectrometry for human melanocortin peptides in vitro and in vivo suggests prominent roles for β-MSH and desacetyl α-MSH in energy homeostasis

Objective: The lack of pro-opiomelanocortin (POMC)-derived melanocortin peptides results in hypoadrenalism and severe obesity in both humans and rodents that is treatable with synthetic melanocortins. However, there are significant differences in POMC processing between humans and rodents, and littl...

Full description

Saved in:
Bibliographic Details
Main Authors: Peter Kirwan (Author), Richard G. Kay (Author), Bas Brouwers (Author), Vicente Herranz-Pérez (Author), Magdalena Jura (Author), Pierre Larraufie (Author), Julie Jerber (Author), Jason Pembroke (Author), Theresa Bartels (Author), Anne White (Author), Fiona M. Gribble (Author), Frank Reimann (Author), I. Sadaf Farooqi (Author), Stephen O'Rahilly (Author), Florian T. Merkle (Author)
Format: Book
Published: Elsevier, 2018-11-01T00:00:00Z.
Subjects:
Online Access:Connect to this object online.
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

Connect to this object online.

3rd Floor Main Library

Holdings details from 3rd Floor Main Library
Call Number: A1234.567
Copy 1 Available