Development of rotational intraperitoneal pressurized aerosol chemotherapy to enhance drug delivery into the peritoneum

• Main Authors: Soo Jin Park (Author), Eun Ji Lee (Author), Hee Su Lee (Author), Junsik Kim (Author), Sunwoo Park (Author), Jiyeon Ham (Author), Jaehee Mun (Author), Haerin Paik (Author), Hyunji Lim (Author), Aeran Seol (Author), Ga Won Yim (Author), Seung-Hyuk Shim (Author), Beong-Cheol Kang (Author), Suk Joon Chang (Author), Whasun Lim (Author), Gwonhwa Song (Author), Jae-Weon Kim (Author), Nara Lee (Author), Ji Won Park (Author), Jung Chan Lee (Author), Hee Seung Kim (Author), On behalf of the KoRIA* trial group (Author)
• Format: Book
• Published: Taylor & Francis Group, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This study aims to evaluate the drug distribution, tissue concentrations, penetration depth, pharmacokinetic properties, and toxicities after rotational intraperitoneal pressurized aerosol chemotherapy (RIPAC) in pigs. Because relevant medical devices have not been introduced, we developed our proto...