Alterations of DNA methylation and expression of genes related to thyroid hormone metabolism in colon epithelium of obese patients

• Главные авторы: Ghazaleh Shimi (Автор), Katayoun Pourvali (Автор), Arman Ghorbani (Автор), Sajad Nooshin (Автор), Shohreh Zare Karizi (Автор), Reza Iranirad (Автор), Hamid Zand (Автор)
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• Опубликовано: BMC, 2022-11-01T00:00:00Z.
• Предметы: article
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Abstract Background Colorectal cancer is common among obese individuals. The purpose of the current study was to determine changes in DNA methylation status and mRNA expression of thyroid hormone receptor beta (THRB), as a tumor suppressor, and thyroid hormone inactivating enzyme, type 3 deiodinase...