Rhinacanthin-C enhances chemosensitivity of breast cancer cells via the downregulation of P-glycoprotein through inhibition of Akt/NF-kappa B signaling pathway

Introduction: High expression of P-glycoprotein (P-gp) has been linked to multidrug resistance (MDR) and chemotherapeutic failure. Previously, we demonstrated that rhinacanthin-C, a naphthoquinone from Rhinacanthus nasutus, was able to enhance the cytotoxicity of doxorubicin against breast cancer MC...

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Main Authors: Suwichak Chaisit (Author), Suree Jianmongkol (Author)
Format: Book
Published: Shahrekord University of Medical Sciences, 2022-01-01T00:00:00Z.
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