Inter-cellular variation in DNA content of Entamoeba histolytica originates from temporal and spatial uncoupling of cytokinesis from the nuclear cycle.

• Hoofdauteurs: Chandrama Mukherjee (Auteur), Shubhra Majumder (Auteur), Anuradha Lohia (Auteur)
• Formaat: Boek
• Gepubliceerd in: Public Library of Science (PLoS), 2009-01-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Accumulation of multiple copies of the genome in a single nucleus and several nuclei in a single cell has previously been noted in Entamoeba histolytica, contributing to the genetic heterogeneity of this unicellular eukaryote. In this study, we demonstrate that this genetic heterogeneity is an inher...