Intrinsic features of Zika Virus non-structural proteins NS2A and NS4A in the regulation of viral replication.

• Main Authors: Yufeng Yu (Author), Chengfeng Gao (Author), Chunxia Wen (Author), Peng Zou (Author), Xian Qi (Author), Carol J Cardona (Author), Zheng Xing (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Zika virus (ZIKV) is a mosquito-borne flavivirus and can cause neurodevelopmental disorders in fetus. As a neurotropic virus, ZIKV persistently infects neural tissues during pregnancy but the viral pathogenesis remains largely unknown. ZIKV has a positive-sense and single-stranded RNA genome, which...