Theophylline attenuates bleomycin-induced oxidative stress in rats: The role of IL-6, NF-κB, and antioxidant enzymes

• Main Authors: Suat Ekin (Author), Serkan Yildirim (Author), Mahire Bayramoglu Akkoyun (Author), Hasya Nazli Gok (Author), Okan Arihan (Author), Gokhan Oto (Author), Turan Akkoyun (Author), Yildiray Basbugan (Author), Sinem Aslan (Author)
• Format: Book
• Published: Universidade de São Paulo, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract The purpose of this study was to evaluate the antifibrotic and antioxidant roles of theophylline (Theo), a bioactive compound, in bleomycin (BLM)-induced pulmonary fibrosis in Wistar albino rats. Assigned into 4 groups were 32 Wistar albino rats, comprising the control group (administered 0...