Soluble Markers of Immune Activation Differentially Normalize and Selectively Associate with Improvement in AST, ALT, Albumin, and Transient Elastography During IFN-Free HCV Therapy

• Main Authors: Lenche Kostadinova (Author), Carey L. Shive (Author), Elizabeth Zebrowski (Author), Brianna Fuller (Author), Kelsey Rife (Author), Amy Hirsch (Author), Anita Compan (Author), Anita Moreland (Author), Yngve Falck-Ytter (Author), Daniel L. Popkin (Author), Donald D. Anthony (Author)
• Format: Book
• Published: Case Western Reserve University, 2018-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: During chronic hepatitis C virus (HCV) infection, Aspartate Aminotransferase (AST) and Alanine Aminotransferase (ALT) levels mark active liver inflammation and tissue damage, while albumin reflects synthetic liver function and nutritional status. Transient Elastography (TE) is a clinical...