Investigation of α,ω-Disubstituted Polyamine-Cholic Acid Conjugates Identifies Hyodeoxycholic and Chenodeoxycholic Scaffolds as Non-Toxic, Potent Antimicrobials

• Үндсэн зохиолчид: Kenneth Sue (Зохиогч), Melissa M. Cadelis (Зохиогч), Thomas Troia (Зохиогч), Florent Rouvier (Зохиогч), Marie-Lise Bo (Зохиогч), Jean Michel Brunel (Зохиогч), Brent R. Copp (Зохиогч)
• Формат: Ном
• Хэвлэсэн: MDPI AG, 2023-02-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

With the increased incidence of antibiotic resistance, the discovery and development of new antibacterials is of increasing importance and urgency. The report of the natural product antibiotic squalamine in 1993 has stimulated a lot of interest in the study of structurally simplified cholic acid-pol...