Investigation of α,ω-Disubstituted Polyamine-Cholic Acid Conjugates Identifies Hyodeoxycholic and Chenodeoxycholic Scaffolds as Non-Toxic, Potent Antimicrobials

• Những tác giả chính: Kenneth Sue (Tác giả), Melissa M. Cadelis (Tác giả), Thomas Troia (Tác giả), Florent Rouvier (Tác giả), Marie-Lise Bo (Tác giả), Jean Michel Brunel (Tác giả), Brent R. Copp (Tác giả)
• Định dạng: Sách
• Được phát hành: MDPI AG, 2023-02-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

With the increased incidence of antibiotic resistance, the discovery and development of new antibacterials is of increasing importance and urgency. The report of the natural product antibiotic squalamine in 1993 has stimulated a lot of interest in the study of structurally simplified cholic acid-pol...