Population Pharmacokinetics and Dosing Regimen of Lithium in Chinese Patients With Bipolar Disorder

• Main Authors: Zi-bin Jin (Author), Zhuo Wu (Author), Yi-fan Cui (Author), Xue-peng Liu (Author), Hong-bo Liang (Author), Jia-yong You (Author), Chen-yu Wang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Lithium is an effective medication approved for the treatment of bipolar disorder (BD). It has a narrow therapeutic index (TI) and requires therapeutic drug monitoring. This study aimed to conduct a population pharmacokinetics (PPK) analysis of lithium and investigate the appropriateness...