TLR9 activation dampens the early inflammatory response to Paracoccidioides brasiliensis, impacting host survival.

• Main Authors: João Filipe Menino (Author), Margarida Saraiva (Author), Ana G Gomes-Alves (Author), Diogo Lobo-Silva (Author), Mark Sturme (Author), Jéssica Gomes-Rezende (Author), Ana Laura Saraiva (Author), Gustavo H Goldman (Author), Cristina Cunha (Author), Agostinho Carvalho (Author), Luigina Romani (Author), Jorge Pedrosa (Author), António Gil Castro (Author), Fernando Rodrigues (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND: Paracoccidioides brasiliensis causes paracoccidioidomycosis, one of the most prevalent systemic mycosis in Latin America. Thus, understanding the characteristics of the protective immune response to P. brasiliensis is of interest, as it may reveal targets for disease control. The initiat...