Creatine Supplementation Potentiates Exercise Protective Effects against Doxorubicin-Induced Hepatotoxicity in Mice

• Main Authors: Loriane R. L. Costa Godinho (Author), Paola S. Cella (Author), Tatiana A. S. Guimarães (Author), Guilherme H. Dantas Palma (Author), Jonathan H. C. Nunes (Author), Rafael Deminice (Author)
• Format: Book
• Published: MDPI AG, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We tested the hypothesis that creatine supplementation may potentiate exercise's protective effects against doxorubicin-induced hepatotoxicity. Thirty-eight Swiss mice were randomly allocated into five groups: control (C, <i>n =</i> 7), exercised (Ex, <i>n =</i> 7), trea...