Informing the risk assessment related to lactation and drug exposure: A physiologically based pharmacokinetic lactation model for pregabalin

• Main Authors: Cameron Humerickhouse (Author), Michelle Pressly (Author), Zhoumeng Lin (Author), Daphne Guinn (Author), Sherbet Samuels (Author), Elimika Pfuma Fletcher (Author), Stephan Schmidt (Author)
• Format: Book
• Published: Wiley, 2024-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Breastfeeding is important in childhood development, and medications are often necessary for lactating individuals, yet information on the potential risk of infant drug exposure through human milk is limited. Establishing a lactation modeling framework can advance our understanding of this...