Caspase-11 Modulates Inflammation and Attenuates Toxoplasma gondii Pathogenesis

• Main Authors: Sheryl L. Coutermarsh-Ott (Author), John T. Doran (Author), Caroline Campbell (Author), Tere M. Williams (Author), David S. Lindsay (Author), Irving C. Allen (Author)
• Format: Book
• Published: Hindawi Limited, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Toxoplasma gondii is an obligate intracellular parasite that is the etiologic agent responsible for toxoplasmosis. Infection with T. gondii results in activation of nucleotide binding domain and leucine rich repeat containing receptors (NLRs). NLR activation leads to inflammasome formation, the acti...