Integration of single-cell RNA-seq and bulk RNA-seq data to construct and validate a cancer-associated fibroblast-related prognostic signature for patients with ovarian cancer

• প্রধান লেখক: Liang Shen (লেখক), Aihua Li (লেখক), Jing Cui (লেখক), Haixia Liu (লেখক), Shiqian Zhang (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: BMC, 2024-04-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Abstract Background To establish a prognostic risk profile for ovarian cancer (OC) patients based on cancer-associated fibroblasts (CAFs) and gain a comprehensive understanding of their role in OC progression, prognosis, and therapeutic efficacy. Methods Data on OC single-cell RNA sequencing (scRNA-...